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Biochip helps to keep bugs at bay
 
The Biochip can detect
and contain infectious diseases quickly.
 
With a recent innovation from the local medical field, we may very well
be looking forward to early detection and better containment of
infectious diseases.

The Genetic Laboratory Biochip, developed by Attogenix Biosystems, can detect infectious diseases in their early stages as well as provide rapid and reliable genetic-based health screening for the masses.

More diagnostic instruments needed
The development of the Biochip stemmed from the need for
adequate diagnostic instruments to aid in preventing and containing infectious diseases.

The World Disasters Report 2000 highlighted that the greatest causes of death worldwide were infectious diseases. In 1999 alone, 13 million perished from diseases such as AIDS, malaria, respiratory illness
and diarrhoea.

Closer to home, the outbreak of SARS highlighted the importance to detect infectious diseases early so that outbreaks can be isolated
and contained.

There is thus a need for a diagnostic instrument that can screen large numbers of people reliably and cost effectively.

Vital support from TEC
An adequate supply of funds was required to keep the Attogenix
project going.

The Enterprise Challenge (TEC), which provides funds for innovative proposals with the potential to create new value or significant improvements to the delivery of public services, provided $333,380 for trial testing the innovation.

However, TEC’s support did not stop at providing capital. Said Dr Farid Ghadessy, Chief Scientist at Attogenix: “TEC has (also) helped by organising the Global Entropolis event which we participated in
last year. This event allowed for a global exposure of the Attogenix diagnostic platform.”

First in the world
The Biochip is a patent-pending technology comprising the Microfluidics Reaction Array Biochip and the Integrated Molecular Analyser.

The product is the world’s first portable diagnostic tool that enables a large number of contamination-free genetic bio-analyses using a novel microfluidics technology.

Said Dr Ghadessy: “The trial was a success, and the results are shortly to be submitted for publication in an international peer-reviewed journal.

“We aim for the Biochip to be the gold standard in diagnostics, available at point-of-care and enabling better patient management for clinicians.”

Benefits of the Biochip
The Genetic Laboratory Biochip will enable the current complicated
PCR lab process in hospitals to be automated and integrated in a
single machine.

Said Dr Ghadessy: “Unlike other systems, the Biochip does not use external pumps, valves or centrifuges. The Biochip allows the chemicals that are required to detect a specific virus or bacteria to be incorporated during manufacture. This reduces contamination issues significantly and allows for numerous viruses and bacteria to be detected simultaneously.”

Advantages over the competition
Biochip is superior to competitors’ products as it allows for large numbers of simultaneous analyses. All its procedures are fully automated and integrated.

Furthermore, the patent-pending microfluidic technology does not require on-chip micro-equipment and performs rapid fluid distribution to prevent cross contamination.

While other products can only be used with at most one other
diagnostic technique, the Biochip can be used for several other diagnostic techniques such as SDA, RT-PCR, IFA, ELISA, protein and cell analysis.
 
 
By TEC
 
 
     
 
 
 
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